Reports

5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus

Science  04 Feb 1983:
Vol. 219, Issue 4584, pp. 503-505
DOI: 10.1126/science.6297002

Abstract

The 5' nucleotide sequences of the transforming gene of simian sarcoma virus (v-sis) and its human cellular homolog (c-sis) were compared. A short homology was found between helper virus and cellular DNA sequences at the junction of v-sis and c-sis, which may have had a role in the original recombination event leading to the generation of simian sarcoma virus.