Specific reading disability: identification of an inherited form through linkage analysis

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Science  18 Mar 1983:
Vol. 219, Issue 4590, pp. 1345-1347
DOI: 10.1126/science.6828864


Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.