Endogenous opiates mediate radiogenic behavioral change

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Science  10 Jun 1983:
Vol. 220, Issue 4602, pp. 1185-1187
DOI: 10.1126/science.6857244


Exposure of C57BL/6J mice to ionizing radiation caused stereotypical locomotor hyperactivity similar to that produced by morphine. Naloxone administration prevented this radiation-induced behavioral activation. These results support the hypothesis that endorphins are involved in some aspects of radiogenic behavioral change.