Reports

Antipyretic potency of centrally administered alpha-melanocyte stimulating hormone

Science  08 Jul 1983:
Vol. 221, Issue 4606, pp. 192-193
DOI: 10.1126/science.6602381

Abstract

Centrally administered alpha-melanocyte stimulating hormone is much more potent in reducing fever than the widely used antipyretic acetaminophen. This finding supports the hypothesis that the endogenous neuropeptide has a role in the limitation of fever and suggests that it may be clinically useful as an antipyretic.