Electrical synapse formation depends on interaction of mutually growing neurites

Science  29 Jul 1983:
Vol. 221, Issue 4609, pp. 466-468
DOI: 10.1126/science.6867723


A neuron's competence to form electrical synapses depends on its growth status. Experiments in situ and in cell culture with identified neurons of the snail Helisoma demonstrate that active neurite outgrowth from both potential partners must be spatially and temporally coincident for electrical synapse formation to occur.