Effects of serotonin on memory impairments produced by ethanol

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Science  29 Jul 1983:
Vol. 221, Issue 4609, pp. 472-474
DOI: 10.1126/science.6223371


Subjects treated with low or high doses of ethanol demonstrated impaired memory, particularly in tests involving the recall of poorly learned information. Zimelidine, an inhibitor of serotonin reuptake, reversed this ethanol-induced impairment. The serotonin neurotransmitter system may mediate learning and memory in humans and may determine some of the effects of alcohol on higher mental functions.