Siphonodictidine, a Metabolite of the Burrowing Sponge Siphonodictyon sp. That Inhibits Coral Growth

Science  16 Sep 1983:
Vol. 221, Issue 4616, pp. 1175-1176
DOI: 10.1126/science.221.4616.1175


Siphonodictidine is the major secondary metabolite of an undescribed Indo-Pacific sponge Siphonodictyon sp. that burrows into living coral heads. The structure of siphonodictidine was determined from spectral data. Laboratory bioassays suggest that siphonodictidine and, by analogy, the siphonodictyals from S. coralliphagum are responsible for maintaining zones of dead coral polyps around the oscular chimneys of these sponges.