Articles

Imaging dopamine receptors in the human brain by positron tomography

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Science  23 Sep 1983:
Vol. 221, Issue 4617, pp. 1264-1266
DOI: 10.1126/science.6604315

Abstract

Neurotransmitter receptors may be involved in a number of neuropsychiatric disease states. The ligand 3-N-[11C]methylspiperone, which preferentially binds to dopamine receptors in vivo, was used to image the receptors by positron emission tomography scanning in baboons and in humans. This technique holds promise for noninvasive clinical studies of dopamine receptors in humans.