Crystals of the octameric histone core of the nucleosome

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Science  27 Jan 1984:
Vol. 223, Issue 4634, pp. 413-414
DOI: 10.1126/science.6691154


The undegraded core histone octamer has been crystallized in a form suitable for x-ray analysis. The hexagonal bipyramidal crystals reproducibly grow larger than 1.0 by 0.6 millimeter, X-ray reflections are observed from Bragg planes with spacings larger than 3.5 angstroms. The crystals have the symmetry of the space group P3l21 or its enantiomorph. There appears to be one histone octamer per asymmetric unit.