Reports

Identification of an erythrocyte component carrying the Duffy blood group Fya antigen

Science  10 Feb 1984:
Vol. 223, Issue 4636, pp. 597-599
DOI: 10.1126/science.6695171

Abstract

The erythrocyte component carrying the Duffy blood group antigen Fya has been identified as a 35- to 43-kilodalton protein. The protein is degraded by proteases, chymotrypsin, and Pronase, which destroy its antigenicity on intact erythrocytes. Its unusual property of aggregating on being boiled in 5 percent sodium dodecyl sulfate with 5 percent 2-mercaptoethanol distinguishes it from other erythrocyte membrane proteins described to date.

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