Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon

Science  16 Mar 1984:
Vol. 223, Issue 4641, pp. 1195-1197
DOI: 10.1126/science.6322297


Antibodies reactive with proteins of human T-cell leukemia virus (HTLV) can be found in Old World monkeys. A T-lymphocyte cell line established from a seropositive baboon (Papio cynocephalus) was analyzed for the presence of viral DNA sequences. The provirus found in these cells was related to but distinct from HTLV subgroup I. These results add to recent evidence from human studies that HTLV represents a spectrum of infectious T-lymphotropic retroviruses that includes closely and distantly related members.