Soluble lectins: a new class of extracellular proteins

Science  23 Mar 1984:
Vol. 223, Issue 4642, pp. 1259-1264
DOI: 10.1126/science.6367039


Soluble lectins of cellular slime molds and vertebrates are present at extracellular sites in the developing or adult tissues that make them. Some lectins are concentrated around cell groups, as in extracellular matrix or elastic fibers. Others are at the interface between cells and the external environment, as in mucin or slime. Specific glycoproteins, proteoglycans, or polysaccharides that bind these endogenous lectins may also be present at these sites. Interactions between the lectins and glycoconjugates appear to play a role in shaping extracellular environments.