Sequential interaction of glia maturation factor with insulin

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Science  30 Mar 1984:
Vol. 223, Issue 4643, pp. 1419-1420
DOI: 10.1126/science.6367047


Astroblasts in culture proliferated when exposed to glia maturation factor for at least 2 hours and then to insulin, but not when exposed in the reverse order. The sequential relation suggests that glia maturation factor is a competence factor.