ReportsLife Sciences

Prolonged weightlessness and humoral immunity

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Science  13 Jul 1984:
Vol. 225, Issue 4658, pp. 214-215
DOI: 10.1126/science.6729476

Abstract

Preflight, inflight, and postflight serum samples obtained from crewmen aboard STS-9 were analyzed for immunoglobulin content. Control studies for circadian rhythm were conducted to further validate the analyses. Quantitation of immunoglobulins G, M, A, D, and E indicated relatively minor fluctuations in the concentration of each class of immunoglobulin during the experiment. Thus, microgravity effects on immunoglobulin levels during a 10-day flight were considered insignificant.

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