Illumination induces dye incorporation in photoreceptor cells

Science  24 Aug 1984:
Vol. 225, Issue 4664, pp. 851-854
DOI: 10.1126/science.6206565


Illumination of fly photoreceptors in the presence of the fluorescent dye Lucifer yellow initiates incorporation of the dye, which stains each cell down to its synaptic terminal. Unilluminated cells do not become stained. Experiments on animals in vivo show that selected cells can be stained without loss of viability. "Induced endocytosis" provides a plausible mechanism underlying this phenomenon.