Bimolane: structure determination indicates anticancer activity is attributable to ICRF-154

See allHide authors and affiliations

Science  14 Sep 1984:
Vol. 225, Issue 4667, pp. 1165-1166
DOI: 10.1126/science.6474171


X-ray diffraction studies of crystals from samples of bimolane synthesized in China and in the United States showed that the crystals consist of the related compound ICRF-154. Analysis of the results of biological tests did not show any significant differences between the anticancer activity of bimolane and ICRF-154. It appears that the anticancer activity of bimolane is due to ICRF-154.