Rapid expulsion of Trichinella spiralis in suckling rats

Science  05 Oct 1984:
Vol. 226, Issue 4670, pp. 70-72
DOI: 10.1126/science.6474191


Orally administered Trichinella spiralis muscle larvae were rapidly expelled by rat pups suckling an immune dam. The immunity was delivered in the milk; substantial resistance was conferred on normal rat pups suckled for only 24 hours by a Trichinella-immune foster mother. The pups were protected by oral or systemic administration of specific serum antibodies. When infused into a normal lactating dam, these antibodies accumulated in the serum of her suckling pups.