Magnetic resonance imaging of biological specimens by electron paramagnetic resonance of nitroxide spin labels

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Science  01 Feb 1985:
Vol. 227, Issue 4686, pp. 517-519
DOI: 10.1126/science.2981437


Electron paramagnetic resonance imaging was demonstrated on two plant species, Apium graveolens and Coleus blumei. This was accomplished by soaking stems of these plants in the paramagnetic nitroxide imaging agent 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl. The experiments were accomplished at L-band frequency (1.4 to 1.9 gigahertz) with single-turn, flat-loop surface coils. One-dimensional imaging spectra were diagnostic of capillary structure and long-term stability.