Expression of myelin-associated glycoprotein by small neurons of the dorsal root ganglion in chickens

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Science  15 Mar 1985:
Vol. 227, Issue 4692, pp. 1359-1360
DOI: 10.1126/science.2579432


Biochemical and immunocytochemical investigations have shown that myelin-associated glycoprotein (MAG) is exclusively related to myelin and myelin-forming cells in mammals. In the present study it was found that dorsal root ganglia in young chickens display MAG-immunoreactive material in most small sensory neurons. The presence of MAG at the surface of small sensory neurons raises the question of whether this glycoprotein acts as a cell adhesion molecule in lower vertebrates.