Amygdalectomy impairs crossmodal association in monkeys

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Science  03 May 1985:
Vol. 228, Issue 4699, pp. 604-606
DOI: 10.1126/science.3983648


Monkeys trained on both visual and tactual versions of an object memory task (delayed nonmatching-to-sample) received bilateral ablations of either the amygdaloid complex or the hippocampal formation of the brain. Although both groups performed well on the two intramodal versions (visual-to-visual and tactual-to-tactual), the amygdalectomized monkeys were severely impaired relative to the hippocampectomized monkeys on a crossmodal version (tactual-to-visual). The findings suggest that the amygdala is critical for certain forms of crossmodal association and that the loss of such associations underlies many of the bizarre behaviors that make up the Kluver-Bucy syndrome.