Reports

Obesity, overeating, and rapid gastric emptying in rats with ventromedial hypothalamic lesions

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Science  07 Feb 1986:
Vol. 231, Issue 4738, pp. 609-611
DOI: 10.1126/science.3511527

Abstract

Measurements confirm the quantitative theoretical prediction that the autonomic nonendocrine abnormality of rapid daytime gastric emptying is the major primary cause of the obesity resulting from ventromedial hypothalamic lesions in rats. Therapy for obesity could include slowing of stomach emptying.