Reports

A pseudoautosomal gene in man

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Science  07 Nov 1986:
Vol. 234, Issue 4777, pp. 740-743
DOI: 10.1126/science.2877492

Abstract

The X/Y homologous gene MIC2 was shown to exchange between the sex chromosomes, thus demonstrating that it is a pseudoautosomal gene in man. MIC2 recombines with the sex-determining gene(s) TDF at a frequency of 2 to 3 percent. It is the most proximal pseudoautosomal locus thus far described and as such is an important marker for use in studies directed towards the isolation of TDF.