Reports

Myosin rod phosphorylation and the catch state of molluscan muscles

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Science  16 Jan 1987:
Vol. 235, Issue 4786, pp. 334-337
DOI: 10.1126/science.3026049

Abstract

"Catch" is a prolonged state of tension in molluscan smooth muscles shown by mechanical measurements to be associated with the level of protein phosphorylation. Myosin isolated from these muscles is unusual in being phosphorylated in the rod portion by an endogenous kinase, like certain nonmuscle myosins. These findings suggest that the myosin rod is a target for phosphorylation and that this reaction may control the transition from catch to relaxation.