Reports

Light-addressable potentiometric sensor for biochemical systems

Science  27 May 1988:
Vol. 240, Issue 4856, pp. 1182-1185
DOI: 10.1126/science.3375810

Abstract

Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially selectable photoresponse permits the determination of a multiplicity of chemical events with a single semiconductor device.