DNA diagnostics--molecular techniques and automation

Science  14 Oct 1988:
Vol. 242, Issue 4876, pp. 229-237
DOI: 10.1126/science.3051381


Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.