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23 December 1988
Vol 242, Issue 4886

About The Cover

Three-dimensional reconstruction of human epileptic cortex showing a large neuronal nucleus with a large nucleolus (yellow) and surrounded by multiple smaller astrocytic nuclei. The neuron shows an interior and abnormal position of one of the two chromosome 9 centromere signals (red). Astrocytic in situ hybridization signals are depicted either in magenta (pink) or cyan (turquoise) for each cell. See page 1687.