Articles

Managing Insect Resistance to Bacillus thuringiensis Toxins

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Science  27 Nov 1992:
Vol. 258, Issue 5087, pp. 1451-1455
DOI: 10.1126/science.258.5087.1451

Abstract

Bacillus thuringiensis (B.t.) δ-endotoxins provide an alternative to chemical insecticides for controlling many species of pest insects. Recent biotechnological developments offer the promise of even greater use of B.t. toxins in genetically transformed pest-resistant crops. However, the discovery that insects can adapt to these toxins raises concerns about the long-term usefulness of B.t. toxins. Several methods for managing the development of resistance to B.t. toxins have been suggested, but none of these approaches offer clear advantages in all situations.