Patchiness and correlations in DNA sequences

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Science  29 Jan 1993:
Vol. 259, Issue 5095, pp. 677-680
DOI: 10.1126/science.8430316


The highly nonrandom character of genomic DNA can confound attempts at modeling DNA sequence variation by standard stochastic processes (including random walk or fractal models). In particular, the mosaic character of DNA consisting of patches of different composition can fully account for apparent long-range correlations in DNA.