Lipid Tubules: A Paradigm for Molecularly Engineered Structures

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Science  10 Dec 1993:
Vol. 262, Issue 5140, pp. 1669-1676
DOI: 10.1126/science.262.5140.1669


The use of molecular self-assembly to fabricate microstructures suitable for advanced material development is described. Templating techniques that transform biomolecular self-assemblies into rugged and stable nano- and microstructures are described. By using a lipid-based microcylinder (tubule) as a paradigm, the path followed from research and development to emerging technological applications is detailed. This process includes modification of the lipid molecular structure, the formation and subsequent characterization of cylindrical microstructures, the use of these structures as templates for metallization, and the characterization and assessment of these hollow metal microcylinders for several potential applications.