Corrections and Clarifications

Corrections and Clarifications

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Science  11 Mar 1994:
Vol. 263, Issue 5152, pp. 1359
DOI: 10.1126/science.263.5152.1359-b

Abstract

The Research News article "Boning up: Newly isolated proteins heal bad breaks" by Joseph Alper (21 Jan., p. 324) incorrectly attributed the rescue of dpp-minus Drosophila by human bone morphogenic protein (BMP) to the laboratory of Michael Hoffmann. That work was published by the laboratory of William Gelbart at Harvard [R. W. Padgett, J. M. Wozney, W. M. Gelbart, Proc. Nati. Acad. Sci. U.S.A. 90, 2905 (1993)]. The work from Hoffmann's laboratory that pertains to the issue of the functional conservation of BMPs during evolution reported that the Drosophila proteins dpp and 60A that are similar in sequence to the human BMPs are effective in stimulating bone formation in the rat. This work was done in collaboration with T. Kuber Sampath at Creative BioMolecules [T. K. Sampath, K. E. Rashka, J. S. Doctor, R. F. Tucker, F. M. Hoffmann, Proc. Nati. Acad. Sci. U.S.A. 90, 6004 (1993)].