Reports

Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance

+ See all authors and affiliations

Science  11 Aug 1995:
Vol. 269, Issue 5225, pp. 843-846
DOI: 10.1126/science.7638602

Abstract

Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.

Related Content