Research NewsImmunology

Monoclonal Antibodies at Age 20: Promise at Last?

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Science  10 Nov 1995:
Vol. 270, Issue 5238, pp. 915-916
DOI: 10.1126/science.270.5238.915


When they were first produced 2 decades ago, monoclonal antibodies were enthusiastically touted as “magic bullets” that would find wide application in medical therapeutics and diagnostics. But a variety of problems including severe immune reactions prevented them from living up to the early hype. A recent conference on monoclonals and cancer therapy suggests, however, that some of the difficulties are slowly being overcome.