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New Clues Found to How Some People Live With HIV

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Science  10 Nov 1995:
Vol. 270, Issue 5238, pp. 917-918
DOI: 10.1126/science.270.5238.917


Nearly 15 years ago, before tests for HIV had been developed, an infected man donated blood in Sydney, Australia, and seven people received transfusions of his contaminated blood. So far, however, neither the donor nor the recipients have shown any harmful effects. The reason, as a team of researchers reports in this issue of Science (p. 988), appears to be that the virus is missing parts of a gene called nef. This may explain why some people infected with HIV survive for long periods without developing AIDS, and a few researchers are arguing that it may point the way to a vaccine made from an attenuated virus.