newsBreast Cancer

Long-Term Tamoxifen Trial Halted

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Science  08 Dec 1995:
Vol. 270, Issue 5242, pp. 1562
DOI: 10.1126/science.270.5242.1562a


In a blow to a promising treatment for breast cancer, a major trial of long-term treatment with the drug tamoxifen has been halted because of evidence that the drug loses its effectiveness if it is given for more than 5 years. The U.S. National Cancer Institute says more research is needed to determine whether tamoxifen may even increase cancer mortality if given for longer periods.