Research News

Molecular Biology: Obesity: Leptin Receptor Weighs In

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Science  05 Jan 1996:
Vol. 271, Issue 5245, pp. 29
DOI: 10.1126/science.271.5245.29


The biggest news in obesity research over the past year has been “the fat gene”: the gene for leptin, a protein that controls body weight in mice. And 1996 is starting off with news that may be just as big. Last week, a research team reported they have cloned DNA that encodes two related receptors that bind the leptin protein in humans and mice, and which may mediate leptin's effects in the body.