Lord of the Rings: GroES Structure

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Science  12 Jan 1996:
Vol. 271, Issue 5246, pp. 161
DOI: 10.1126/science.271.5246.161


The crystal structure of the chaparonin GroES, which together with GroEL assists in the folding of many proteins in Escherichia coli, is reported in this issue of Science by Mande et al. (p. 203). In this Perspective, M. Mayhew and F. U. Hartl discuss the implications of the new structure for the function of the GroEL:GroES complex.