Developmental Biology: Fertile Results: Bringing Up Baby (Eggs)

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Science  02 Feb 1996:
Vol. 271, Issue 5249, pp. 594
DOI: 10.1126/science.271.5249.594


Biologists are proud to announce two births: a healthy mouse pup and a new era of reproductive biology. The mouse is the first product of an egg grown in vitro all the way from its primordial precursor, or oocyte, to maturity, when it was fertilized. Scientists are excited by the promise of such “oocyte farming”: This means more opportunities for in vitro fertilization—because mammals produce many more oocytes than mature eggs—and a new window on oocyte development.