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15 March 1996
Vol 271, Issue 5255

About The Cover

Cryosection of a yeast nucleus (long axis, 1.6 micrometers) immunolabeled to reveal the sites of the nuclear envelope that are associated with the coat protein coatomer. Antibodies to coatomer were applied to the section, then the bound antibodies were identified in a second step with the help of electron-dense gold particles that appear as tiny dots on the nuclear surface. See 1526, the special section on Protein Kinesis beginning on 1513, and the News story on 1493. [R. Schekman and L. Orci]