Generation of GTP-Ran for Nuclear Protein Import

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Science  05 Apr 1996:
Vol. 272, Issue 5258, pp. 47
DOI: 10.1126/science.272.5258.47


Certain cytoplasmic proteins are actively transported into the nucleus through nuclear pores. In a paper in this week's issue the function of a participating soluble protein, p10, is elucidated (Nehrbass and Blobel, p. 120). Moore explains, in her Perspective, how these findings solve the riddle of the source of one of the molecules required for transport, GTP-Ran.