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Worm Genes Imply a Master Clock

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Science  17 May 1996:
Vol. 272, Issue 5264, pp. 949-950
DOI: 10.1126/science.272.5264.949


New research reported in this issue of Science (p. 1010) reveals a set of genes, the clk genes, that when mutated can make a worm live life in slow motion, swimming and eating more slowly than usual. And these experimental worms also live longer; worms with combinations of mutations lived five times as long as normal, the greatest increase in life-span ever seen in any organism. Researchers hope the new work will yield clues to aging in more complex organisms as well.