24 May 1996
Vol 272, Issue 5265

About The Cover

Waves of spontaneous neural activity create domains in the developing mammalian retina. Activity was detected in the retinal ganglion cell layer of a newborn ferret by fluorescence imaging with a calcium indicator. The gray background is a fluorescence image of a P2 retina. The colors correspond to six consecutive waves that occurred during 1 minute of imaging, and the intensity indicates the direction of propagation (dark to light). See 1182. [Image: M. B. Feller, D. P. Wellis, D. Stellwagen, F. S. Werblin, and C. J. Shatz]