Research NewsCytogenetics

New Methods for Expanding the Chromosomal Paint Kit

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Science  26 Jul 1996:
Vol. 273, Issue 5274, pp. 430
DOI: 10.1126/science.273.5274.430


Two groups of researchers, one of which reports its results on page 494, have found a way to tag chromosomes with fluorescent markers so that each chromosome can be depicted by a computer as having a distinctive color. The techniques are likely to be useful for detecting chromosomal rearrangements and other abnormalities in cancer cells, and in screening for defects that underlie genetic disorders such as Down syndrome.