Research NewsNeurobiology

Glimpsing Myelin's Protein Glue

+ See all authors and affiliations

Science  20 Sep 1996:
Vol. 273, Issue 5282, pp. 1657-1658
DOI: 10.1126/science.273.5282.1657

Summary

The rapid transmission of nerve signals in higher animals would not be possible if thenerves didn't have their insulating covering of myelin. Now determination of the structure of a key myelin protein, called P0, has helped explain how the tightly wrapped membranous layers that form the myelin are held together and also how some mutations weaken the glue, leading to neurological disease.