A Chloride Channel Model?

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Science  01 Nov 1996:
Vol. 274, Issue 5288, pp. 738
DOI: 10.1126/science.274.5288.738


Miller explains in his Perspective [also see report by Malashkevich et al. (p. 761)] why the new pentameric coiled-coil structure of the extracellular matrix protein COMP is exciting for students of ion channels. The narrow channel created by the coils holds not only water but a chloride ion.