Research NewsCell Biology

The Telomerase Picture Fills In

Science  25 Apr 1997:
Vol. 276, Issue 5312, pp. 528-529
DOI: 10.1126/science.276.5312.528

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Summary

Researchers may finally have nailed a long-sought quarry: a catalytic protein that helps rebuild the chromosome ends after each cell division. In work described on page 561, researchers report that they have isolated a catalytic component of the enzyme telomerase from both a ciliated protozoan called Euplotes aediculatus and yeast. Although there are other candidates for the protein, other telomerase researchers find the evidence for this one particularly convincing. If so, the discovery will not only provide a boost to researchers trying to understand how it does its crucial job, but could also lead to insights into aging and cancer.