Special Articles

Microbial Pathogenesis: Genomics and Beyond

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Science  02 May 1997:
Vol. 276, Issue 5313, pp. 707-712
DOI: 10.1126/science.276.5313.707

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Abstract

The growing number of complete microbial genome sequences provides a powerful tool for studying the biology of microorganisms. In combination with assays for function, genomic-based approaches can facilitate efficient and directed research strategies to elucidate mechanisms of bacterial pathogenicity. As genomic information accrues, the challenge remains to construct a picture of the biology that accurately reflects how individual genes collaborate to create the complex world of microbial specialization.

  • * To whom correspondence should be addressed. E-mail: estrauss{at}cmgm.stanford.edu

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