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Antisense Aims for a Renaissance

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Science  23 May 1997:
Vol. 276, Issue 5316, pp. 1192-1193
DOI: 10.1126/science.276.5316.1192

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Summary

CAMBRIDGE, MASSACHUSETTS-- Once plagued by side effects and mysterious failures, antisense technologies are now shedding their troubled image. Basic research has uncovered explanations--and solutions--to some of the earlier problems, and antisense drugs have shown promise in early clinical trials against cancer and Crohn's disease.