Report

Genetic Feminization of Pheromones and Its Behavioral Consequences in Drosophila Males

Science  06 Jun 1997:
Vol. 276, Issue 5318, pp. 1555-1558
DOI: 10.1126/science.276.5318.1555

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Abstract

Pheromones are intraspecific chemical signals important for mate attraction and discrimination. In the fruit fly Drosophila melanogaster, hydrocarbons on the cuticular surface of the animal are sexually dimorphic in both their occurrence and their effects: Female-specific molecules stimulate male sexual excitation, whereas the predominant male-specific molecule tends to inhibit male excitation. Complete feminization of the pheromone mixture produced by males was induced by targeted expression of the transformer gene in adult oenocytes (subcuticular abdominal cells) or by ubiquitous expression during early imaginal life. The resulting flies generally exhibited male heterosexual orientation but elicited homosexual courtship from other males.

  • * To whom correspondence should be addressed. E-mail: ferveur{at}ext.jussieu.fr

  • Present address: The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121, USA.

View Full Text

Cited By...