Mariner Sails into Leishmania

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Science  13 Jun 1997:
Vol. 276, Issue 5319, pp. 1659-1660
DOI: 10.1126/science.276.5319.1659

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Daniel L. Hartl Transposons are bits of DNA that can move from place to place in the genomes of plants and animals. The wide-ranging transposon mariner is found in many different animals, and in this issue Gueiros-Filho and Beverley show that, given the right circumstances, it can also move into the genome of Leishmania, the cause of a deadly disease in the tropics. In his Perspective, Hartl explains the features of this transposable element and how the ability to move it into the Leishmania genome will increase the tools available in the search for a treatment for this pathogen.