Research News

Causing Cancer by Remote Control?

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Science  20 Jun 1997:
Vol. 276, Issue 5320, pp. 1788-1789
DOI: 10.1126/science.276.5320.1788

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Despite decades of trying, researchers have been able to link only a few cancers to possible viral causes. Now, in work described on page 1851, they've added a new one to the list. The bone marrow cancer called multiple myeloma has been linked to Kaposi's sarcoma-associated herpesvirus (KSHV), which is already under suspicion as the cause of Kaposi's sarcoma, a cancer that afflicts many AIDS patients. But unlike all the other viruses linked to cancers, KSHV appears to propel the growth of myeloma tumors not from within the tumor cells themselves, but from within neighboring normal cells.